Thomas and his young friends are coming to terms with the realisation that their blood could hold the key to unlocking a cure to the deadly Flare contagion. Defying the advice of other survivors, Thomas pledges to rescue his captured friend Minho from the clutches of the World Catastrophe Killzone Department (W.C.K.D.) and its Machiavellian lead physician, Ava Paige. Newt, Frypan, Brenda and her surrogate father Jorge join Thomas on the daredevil mission.
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